Spray-Dried Porcine Plasma Promotes the Association Between Metabolic and Immunological Processes at Transcriptional Level in Gilthead Sea Bream (Sparus aurata) Gut

نویسندگان

چکیده

The spray-dried porcine plasma (SDPP) is an abattoir by-product used in animal nutrition with beneficial effects reported livestock and commercial aquatic species. Previous results have found that the dietary inclusion of SDPP gilthead sea bream ( Sparus aurata ) increased density intestinal goblet cells, it did not result significant changes autochthonous microbiota. However, there no comprehensive data on mechanisms could take place intestine fed SDPP-supplemented diet. For this reason, study aimed to unveil biological modulated response administration gut. To achieve goal, we made a microarrays-based transcriptomic approach gut samples from diet for 95 days. As control diet, protein-rich feed (51% crude protein, 17% fat, 20.6 MJ/kg gross energy) which was supplemented 3% at expense LT70 fishmeal. microarray analyses showed total 803 (468 up- 335 down-regulated) differential expressed genes (DEGs). functional network analysis revealed induced sustained 120 processes, grouped 12-clusters. Among them, metabolic-related process (cellular catabolic process, organic substance protein metabolism process), transport, leukocyte mediated immunity interacted leading interactome network. This evidence confirms previous enhancement mucosal health status provides further understanding mode action ingredient aquafeeds.

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ژورنال

عنوان ژورنال: Frontiers in Marine Science

سال: 2022

ISSN: ['2296-7745']

DOI: https://doi.org/10.3389/fmars.2022.814233